Showing posts with label H5N1 symptoms. Show all posts
Showing posts with label H5N1 symptoms. Show all posts

Tuesday, October 02, 2007

Will Pandemic H5N1 Kill Humans In This Way?

1918 : The Horrifically Gruesome Death Of 'Spanish Flu' Victims


An horrifically gruesome, descriptive passage of what happens when a human dies from bird flu, from Michael Greger's extraordinary online book about H5N1, and the likelihood of a re-occurence of the 1918-1919 Spanish Flu pandemic :
What started for millions around the globe as muscle aches and a fever ended days later with many victims bleeding from their nostrils, ears, and eye sockets. Some bled inside their eyes; some bled around them. They vomited blood and coughed it up. Purple blood blisters appeared on their skin.

The Chief of the Medical Services, Major Walter V. Brem, described the horror at the time in the Journal of the American Medical Association. He wrote that “often blood was seen to gush from a patient’s nose and mouth.” In some cases, blood reportedly spurted with such force as to squirt several feet. “When pneumonia appeared,” Major Brem recounted, “the patients often spat quantities of almost pure blood.” They were bleeding into their lungs.

As victims struggled to clear their airways of the bloody froth that poured from their lungs, their bodies started to turn blue from the lack of oxygen, a condition known as violaceous heliotrope cyanosis. “They’re as blue as huckleberries and spitting blood,” one New York City physician told a colleague. U.S. Army medics noted that this was “not the dusky pallid blueness that one is accustomed to in failing pneumonia, but rather [a] deep blueness…an indigo blue color.” The hue was so dark that one physician confessed that “it is hard to distinguish the colored men from the white.” “It is only a matter of a few hours then until death comes,” recalled another physician, “and it is simply a struggle for air until they suffocate.” They drowned in their own bloody secretions.

“It wasn’t always that quick, either,” one historian adds. “And along the way, you had symptoms like fingers and genitals turning black, and people reporting being able to literally smell the body decaying before the patient died.” “When you’re ill like that you don’t care,” recalls one flu survivor, now 100 years old. “You don’t care if you live or die.”

Major Brem described an autopsy: “Frothy, bloody serum poured from the nose and mouth when the body was moved, or the head lowered…. Pus streamed from the trachea when the lungs were removed.” Fellow autopsy surgeons discussed what they called a “pathological nightmare,” with lungs up to six times their normal weight, looking “like melted red currant jelly.” An account published by the National Academies of Science describes the lungs taken from victims as “hideously transformed” from light, buoyant, air-filled structures to dense sacks of bloody fluid.

There was one autopsy finding physicians reported having never seen before. As people choked to death, violently coughing up as much as two pints of yellow-green pus per day, their lungs would sometimes burst internally, forcing air under pressure up underneath their skin. In the Proceedings of the Royal Society of Medicine, a British physician noted “one thing that I have never seen before—namely the occurrence of subcutaneous emphysema”—pockets of air accumulating just beneath the skin—“beginning in the neck and spreading sometimes over the whole body.”

These pockets of air leaking from ruptured lungs made patients crackle when they rolled onto their sides. In an unaired interview filmed for a PBS American Experience documentary on the 1918 pandemic, one Navy nurse compared the sound to a bowl of Rice Krispies. The memory of that sound—the sound of air bubbles moving under people’s skin—remained so vivid that for the rest of her life, she couldn’t be in a room with anyone eating that popping cereal.
There seems to be limited information, online at least, about whether the hundreds of people who have already died of bird flu suffered deaths in any way similar to those detailed above.

Saturday, September 29, 2007

Unborn Babies Can Catch Bird Flu From Their Mothers

Disturbing news from a study published in The Lancet. Not only does H5N1 attack the lungs, brain and other key organs, it can also infect foetuses.

InsiderMedicine has some more on this, and provides 'important points to remember for medical staff who may find themselves dealing with bird flu patients :
• Influenza A H5N1 should be considered in patients who are febrile with an URTI and a know history of exposure to sick or dead poultry, wild birds, other ill people, travel to an endemic area, or in someone whose work entails handling samples.

• Isolating all hospitalized patients who are under evaluation for influenza A, following the same precautions as those used for severe acute respiratory syndrome, or SARS. This includes a room with negative air pressure, and contacts gowning, gloving and using eye shields.

• Viral replication is long, and has been noted to continue up to 15-17 days following onset of symptoms. The virus has been detected in respiratory secretions, saliva, blood and stools.

Researchers from Beijing University studied tissue from a man, a woman, and her fetus to determine how the virus affects different organs in the body. The two adults had died as a result of the bird flu virus.

The researchers were able to detect the H5N1 virus in the lungs, throat, lymph nodes, brain cells, and in the cells of the placenta. In the fetus, both viral genetic material and antigens were found in the lungs, and immune system and liver cells.

Go Here To Read The Full Insider Medicine Story

Friday, September 28, 2007

Will Pandemic H5N1 Kill Humans In This Way?

1918 : The Horrifically Gruesome Death Of 'Spanish Flu' Victims


An horrifically gruesome, descriptive passage of what happens when a human dies from bird flu, from Michael Greger's extraordinary online book about H5N1, and the likelihood of a re-occurence of the 1918-1919 Spanish Flu pandemic :
What started for millions around the globe as muscle aches and a fever ended days later with many victims bleeding from their nostrils, ears, and eye sockets. Some bled inside their eyes; some bled around them. They vomited blood and coughed it up. Purple blood blisters appeared on their skin.

The Chief of the Medical Services, Major Walter V. Brem, described the horror at the time in the Journal of the American Medical Association. He wrote that “often blood was seen to gush from a patient’s nose and mouth.” In some cases, blood reportedly spurted with such force as to squirt several feet. “When pneumonia appeared,” Major Brem recounted, “the patients often spat quantities of almost pure blood.” They were bleeding into their lungs.

As victims struggled to clear their airways of the bloody froth that poured from their lungs, their bodies started to turn blue from the lack of oxygen, a condition known as violaceous heliotrope cyanosis. “They’re as blue as huckleberries and spitting blood,” one New York City physician told a colleague. U.S. Army medics noted that this was “not the dusky pallid blueness that one is accustomed to in failing pneumonia, but rather [a] deep blueness…an indigo blue color.” The hue was so dark that one physician confessed that “it is hard to distinguish the colored men from the white.” “It is only a matter of a few hours then until death comes,” recalled another physician, “and it is simply a struggle for air until they suffocate.” They drowned in their own bloody secretions.

“It wasn’t always that quick, either,” one historian adds. “And along the way, you had symptoms like fingers and genitals turning black, and people reporting being able to literally smell the body decaying before the patient died.” “When you’re ill like that you don’t care,” recalls one flu survivor, now 100 years old. “You don’t care if you live or die.”

Major Brem described an autopsy: “Frothy, bloody serum poured from the nose and mouth when the body was moved, or the head lowered…. Pus streamed from the trachea when the lungs were removed.” Fellow autopsy surgeons discussed what they called a “pathological nightmare,” with lungs up to six times their normal weight, looking “like melted red currant jelly.” An account published by the National Academies of Science describes the lungs taken from victims as “hideously transformed” from light, buoyant, air-filled structures to dense sacks of bloody fluid.

There was one autopsy finding physicians reported having never seen before. As people choked to death, violently coughing up as much as two pints of yellow-green pus per day, their lungs would sometimes burst internally, forcing air under pressure up underneath their skin. In the Proceedings of the Royal Society of Medicine, a British physician noted “one thing that I have never seen before—namely the occurrence of subcutaneous emphysema”—pockets of air accumulating just beneath the skin—“beginning in the neck and spreading sometimes over the whole body.”

These pockets of air leaking from ruptured lungs made patients crackle when they rolled onto their sides. In an unaired interview filmed for a PBS American Experience documentary on the 1918 pandemic, one Navy nurse compared the sound to a bowl of Rice Krispies. The memory of that sound—the sound of air bubbles moving under people’s skin—remained so vivid that for the rest of her life, she couldn’t be in a room with anyone eating that popping cereal.


There seems to be limited information, online at least, about whether the hundreds of people who have already died of bird flu suffered deaths in any way similar to those detailed above.